Erythrophagocytosis induced ferroptosis contribute to pulmonary microvascular thrombosis and thrombotic vascular remodeling in pulmonary arterial hypertension

Whether primary or just as a complication from the progression of pulmonary arterial hypertension (PAH), thrombosis seems to be an important player in this condition. The cross-talk between red blood cells (RBCs) and pulmonary microvascular endothelial cells (PMVECs) and their role in PAH remain undefined.