脱颗粒
肥大细胞
化学
桅杆（植物学）
细胞生物学
药理学
免疫学
生物
受体
生物化学
作者
Joshua Wollam,Michelle Solomon,Christiane Villescaz,Marion Lanier,Samantha Evans,Corinne Bacon,David E. Freeman,Alexis Vasquez,Alan Vest,Jim Napora,Brittney Charlot,Christine Cavarlez,Andrew Kim,Lisa Dvorak,Brandon Selfridge,Li‐Min Huang,Andres Nevarez,Harry Dedman,Jennifer Brooks,Stefan Frischbutter
标识
DOI：10.1016/j.jaci.2024.07.002
摘要
MRGPRX2 small molecule antagonists potently inhibited agonist-induced mast cell degranulation in vitro and in vivo as well as ex vivo in human skin, supporting potential therapeutic utility as a novel treatment for multiple human diseases involving clinically relevant mast cell activation.
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(2025-6-4)
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