Genome-wide screening of genes involved in programming diapause in the next generation in silkworm, Bombyx mori (Lepidoptera: Bombycidae)

The sub-oesophageal ganglion of silkworms is stimulated at an early stage in the development of the pupae to secrete the hormone that induces the production of diapause eggs, but the hormone secretion is programmed before pupation (Fukuda, 1951(Fukuda, , 1952;; Hasegawa, 1951).The transplantation of cultured brains from silkworm larvae indicates that the diapause program is created and memorized in the brain (Hasegawa & Shimizu, 1987).However, it is unclear how information on environmental conditions affects the molecular mechanisms that determine diapause status.The present study aimed to identify genes that are involved in the programming of diapause in next generation eggs in bivoltine silkworms.We postulated that key genes involved in silkworm programming of diapause are differentially expressed in diapause-egg (DEPs) and non-Genome-wide screening of genes involved in programming diapause in the next generation in silkworm, Bombyx mori (Lepidoptera: Bombycidae)