机制(生物学)
癌症研究
免疫系统
卵巢癌
CD44细胞
医学
癌症
钥匙(锁)
免疫学
生物
内科学
物理
细胞
生态学
遗传学
量子力学
作者
Lisha Hou,Mei Jiang,Yue Li,Jin Q. Cheng,Fei Liu,Xiaoyang Han,Jiahao Guo,Lei Feng,Zhefeng Li,Junjie Yi,Xiaoting Zhao,Yan Gao,Wentao Yue
标识
DOI:10.1016/j.intimp.2025.114906
摘要
TAMs drive immune suppression and T-cell exhaustion in ovarian cancer via the SPP1-CD44 axis, highlighting this pathway as a promising therapeutic target for reprogramming the immune microenvironment and improving patient outcomes.
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