医学
神秘的
SMARCA4型
放射科
淋巴结
门(解剖学)
核医学
病理
遗传学
染色质
生物
染色质重塑
替代医学
DNA
作者
Weizhi Xu,Liang Zhao,Jiayu Cai,Haojun Chen
出处
期刊:Clinical Nuclear Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2024-03-25
标识
DOI:10.1097/rlu.0000000000005191
摘要
SMARCA4-deficient undifferentiated tumors (SMARCA4-dUT) are rare and aggressive neoplasms commonly found in male smokers and portend a poor prognosis. In this case, we reported 18F-FDG and 68Ga-FAPI-46 PET/CT findings in an occult SMARCA4-dUT located in the left pulmonary hilum along with mediastinal lymph node metastases. 68Ga-FAPI-46 PET/CT showed superiority over 18F-FDG for detecting SMARCA4-dUT lesions. This case highlighted that 68Ga-FAPI-46 PET/CT may be a promising imaging modality in the evaluation of SMARCA4-dUT, particularly for detecting the occult SMARCA4-dUT arising in uncommon sites.
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