Electrocatalytic Synthesis of Essential Amino Acids from Nitric Oxide Using Atomically Dispersed Fe on N‐doped Carbon

Abstract How to transfer industrial exhaust gases of nitrogen oxides into high‐values product is significantly important and challenging. Herein, we demonstrate an innovative method for artificial synthesis of essential α‐amino acids from nitric oxide (NO) by reacting with α‐keto acids through electrocatalytic process with atomically dispersed Fe supported on N‐doped carbon matrix (AD‐Fe/NC) as the catalyst. A yield of valine with 32.1 μmol mg cat −1 is delivered at −0.6 V vs . reversible hydrogen electrode, corresponding a selectivity of 11.3 %. In situ X‐ray absorption fine structure and synchrotron radiation infrared spectroscopy analyses show that NO as nitrogen source converted to hydroxylamine that promptly nucleophilic attacked on the electrophilic carbon center of α‐keto acid to form oxime and subsequent reductive hydrogenation occurred on the way to amino acid. Over 6 kinds of α‐amino acids have been successfully synthesized and gaseous nitrogen source can be also replaced by liquid nitrogen source (NO 3 − ). Our findings not only provide a creative method for converting nitrogen oxides into high‐valued products, which is of epoch‐making significance towards artificial synthesis of amino acids, but also benefit in deploying near‐zero‐emission technologies for global environmental and economic development.