This study investigates the potential of ultrasound-induced radical generation to accelerate chemical reactions, focusing on the decomposition of hydrogen peroxide (H₂O₂). High-frequency ultrasound creates cavitation bubbles that collapse to produce hydroxyl radicals (•OH), significantly enhancing reaction rates. Our results demonstrate that this approach increases the decomposition rate of H₂O₂ by 400% compared to conventional methods. The implications extend to various applications, including optimizing chemotherapy drug activation and improving wastewater treatment through advanced oxidation processes. Given its scalability and cost-effectiveness, ultrasound-driven radical chemistry has the potential to transform industrial and scientific processes.