早晨
食欲
减肥
卡路里
傍晚
超重
肥胖
内分泌学
体重增加
内科学
医学
热卡限制
基础代谢率
低热量饮食
交叉研究
动物科学
生理学
体重
生物
物理
天文
病理
替代医学
安慰剂
作者
Leonie C. Ruddick-Collins,Peter J. Morgan,C. L. Fyfe,João A. N. Filipe,Graham W. Horgan,Klaas R. Westerterp,Jonathan D. Johnston,Alexandra M. Johnstone
出处
期刊:Cell Metabolism
[Elsevier]
日期:2022-10-01
卷期号:34 (10): 1472-1485.e6
被引量:11
标识
DOI:10.1016/j.cmet.2022.08.001
摘要
Morning loaded calorie intake in humans has been advocated as a dietary strategy to improve weight loss. This is also supported by animal studies suggesting time of eating can prevent weight gain. However, the underlying mechanisms through which timing of eating could promote weight loss in humans are unclear. In a randomized crossover trial (NCT03305237), 30 subjects with obesity/overweight underwent two 4-week calorie-restricted but isoenergetic weight loss diets, with morning loaded or evening loaded calories (45%:35%:20% versus 20%:35%:45% calories at breakfast, lunch, and dinner, respectively). We demonstrate no differences in total daily energy expenditure or resting metabolic rate related to the timing of calorie distribution, and no difference in weight loss. Participants consuming the morning loaded diet reported significantly lower hunger. Thus, morning loaded intake (big breakfast) may assist with compliance to weight loss regime through a greater suppression of appetite.
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