乳腺癌
癌症研究
破骨细胞
谷氨酰胺
癌细胞
转移性乳腺癌
医学
癌症
转移
骨转移
内科学
生物
生物化学
受体
氨基酸
作者
Huijuan Fan,Zhanao Xu,Ke Yao,Bingxin Zheng,Yuan Zhang,Xuxiang Wang,Tengjiang Zhang,Xuan Li,Haitian Hu,Bin Yue,Zeping Hu,Hanqiu Zheng
出处
期刊:Cancer Research
[American Association for Cancer Research]
日期:2023-12-01
卷期号:84 (3): 449-467
被引量:24
标识
DOI:10.1158/0008-5472.can-23-1443
摘要
Metabolic interaction between osteoclasts and tumor cells contributes to resistance to DNA-damaging agents, which can be blocked by combination treatment with PARP and osteoclast inhibitors to reduce bone metastatic burden.
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