医学
扭转
心脏病学
内科学
斑点追踪超声心动图
舒张期
基础(医学)
旋转(数学)
射血分数
几何学
心力衰竭
数学
血压
胰岛素
作者
Michael V. Di Maria,Giuseppe Caracciolo,Steven Prashker,Partho P. Sengupta,Anirban Banerjee
标识
DOI:10.1016/j.echo.2014.07.016
摘要
In children, there is limited information regarding the relative contribution of left ventricular (LV) apical and basal rotation to increase LV pump function with exercise. The aim of this study was to test the hypothesis that a progressive increase in LV pump function with exercise is related to increased LV apical and basal rotation.Forty-two subjects 12 to 18 years of age with normal cardiac structure and function were recruited prospectively and imaged at rest, and in 20 subjects, imaging was repeated after moderate exercise. Conventional measures of LV systolic and diastolic performance were evaluated. Left ventricular rotation, LV twist, rotational rate, and recoil and untwist rates were measured using two-dimensional speckle-tracking echocardiography. Torsion was calculated by normalizing LV twist to LV diastolic length. Twist displacement loops were constructed from data obtained at rest and after exercise.Apical rotation increased significantly after exercise (7.33 ± 2.8° vs 11.6 ± 4.7°, P = .0004), but basal rotation did not (-4.85 ± 1.9 vs -6.46 ± 4.81, P = .21). Similarly, peak twist, torsion, and twist rate also increased significantly after exercise. In diastole, apical recoil rate and LV untwist rate also increased significantly with exercise. The slope of the systolic limb of the twist displacement loop and the area enclosed by the loop also increased significantly with exercise.Increases in global LV pump function during exercise in children are associated with enhanced LV apical rotation but not LV basal rotation. In addition, unique changes were seen in twist displacement loops in children before and after exercise. These data may serve as a foundation for understanding future applications of LV rotational mechanics in disease states.
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