Study on the relationship between serum brain natriuretic peptide,left ventricular ejection fraction and cardiac function in senile patients with coronary heart disease

Objective To investigate the relationship between serum brain natriuretic peptide(BNP),left ventricular ejection fraction(LVEF) and cardiac function in more than 80-year-old patients with coronary heart disease.Methods Serum BNP,LVEF and each cardiac functional class in 222 patients were analyzed with variance analysis method.Correlation analysis was carried out at the same time.Results The cardiac functional class was positively correlated with the serum BNP.The serum BNP levels had a statistically significant differences in patients with different cardiac functional class.The cardiac functional class was negatively correlated with the LVEF.The LVEF had a statistically significant difference in patients with different cardiac functional class.Conclusion The serum BNP and LVEF correlate with cardiac functional class,but neither of them may be a unique diagnosis standard of cardiac functional class.