Ultrasensitive nanosensor based on gold nanoparticles to detect vascular endothelial growth factor (VEGF)

We report on the use of new biosensor that enable a surface Plasmon resonance (SPR) sensor to detec VEGF in tissue extracts and cell lysates. This sensor consist of gold nanoparticles functionalized with antibodies anti-VEGF. To analyze the optical properties and their sensing ability was held optical absorption experiments in band plasmon resonance. We demonstrate that this approach makes it possible for the SPR biosensor to detect VEGF in tissues at low concentrations.