化学
醛
有机化学
组合化学
冷凝
块(置换群论)
级联
有机合成
立体化学
脚手架
功能群
联轴节(管道)
群(周期表)
缩合反应
化学合成
作者
Sampa Mondal,Bibrata Kumar Ghosh,Rabindra Nath Sana,Bidhusree Maity,Soumen Giri,Susanta Kumar Manna
标识
DOI:10.1002/slct.202505976
摘要
ABSTRACT 3‐(2‐formylcycloalkenyl)‐acrylic ester (FCAE) acts as an important building block in synthetic organic chemistry. Co‐existence of α, β‐unsaturated ester and α, β‐unsaturated aldehyde makes it a useful scaffold for the synthesis of diverse carbocyclic and heterocyclic compounds through Michael addition, condensation reaction, coupling reaction, multicomponent reaction, cascade cyclization, functional group conversion, and asymmetric synthesis. The literature covers the area since last couple of decades. In this review, we outline the various pathways for bicyclic, tricyclic, tetracyclic, pentacyclic, and polycyclic heterocyclic scaffolds with their mechanistic details.
科研通智能强力驱动
Strongly Powered by AbleSci AI