Exon Skipping of Ste20- Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production

An alternatively spliced variant of SLK stimulates tumor growth by activating ENO1 to promote phosphoenolpyruvate production and glycolysis, indicating that targeting this splicing alteration is a strategy to overcome cancer metabolic rewiring.