Interstitial lung abnormality in COPD is associated with higher prevalence of antinuclear antibody

OBJECT: To investigate whether the prevalence of positive ANA was increased in COPD with interstitial lung abnormality (ILA). METHODS: Patients with COPD from 1 September, 2019 to 31 August, 2022 were consecutively enrolled in this cross-sectional study. The characteristics, PFTs, visual assessment of ILA and emphysema on chest CT, and tests for ANA and CRP were recorded for analysis. RESULTS: % predicted, FVC, total lung capacity (TLC), and TLC % predicted were significantly lower, as compared to those with negative ANA. CONCLUSION: and lung volume.