Flexible Electrochemical Glucose Sensor Based on PtNPs Modified MXene/SF Membrane

Flexible enzymatic glucose sensors with high selectivity and low environmental pollution are attracting in glucose detection and real-time monitoring. In this study, a flexible enzymatic glucose sensor GOD/PtNPs/MXene/SF was developed for glucose detection. Silk fibroin (SF) and MXene were poured into a flexible and conductive membrane, which then was modified with platinum nanoparticles (PtNPs) by electrochemical deposition. Glucose oxidase (GOD) was immobilized on this PtNPs/MXene/SF composite by crosslinking to prepare the flexible sensor. Thanks to the good electrochemical activity of MXene and the high catalytic effect of PtNPs, the fabricated GOD/PtNPs/MXene/SF sensor showed good sensing performances in glucose detection, with response time less than 10 s, sensitivity of 42.43 μA mM ^-1 cm ^-2 , linear range of 0.12-10 mM and detection limit of 120 μM. Based on the specificity and reproducibility of GOD, this GOD/PtNPs/MXene/SF sensor also exhibited the excellent anti-interference ability, reproducibility and long-term stability, and it had the reliable sensing performance for practical application in glucose detection of human organisms and drinks with the recovery ranging from 96% to 108%. Overall, the fabricated flexible GOD/PtNPs/MXene/SF sensor with reliable and stable sensing performances in this study has a good application prospect for glucose detection and real-time monitoring.