化学
苯并噻吩
醋酸
激进的
溶剂
分子内力
催化作用
有机化学
组合化学
光化学
噻吩
作者
Vighneshwar Bhat,Anna Lee
标识
DOI:10.1002/adsc.202300099
摘要
Abstract A one‐pot, three‐component synthesis of 3‐(arylsulfonyl)benzothiophenes was developed. The reaction did not require any catalysts or additives. The desired products were obtained via an intramolecular radical cyclization. Acetic acid was employed as the solvent and a quencher for side reactions involving methyl radicals. Moreover, inexpensive potassium metabisulfite was used as a sulfur dioxide surrogate. This process provides more opportunities for synthesizing benzothiophene derivatives, which are found in many bioactive compounds. magnified image
科研通智能强力驱动
Strongly Powered by AbleSci AI