Multidimensional Engineering of Escherichia coli for Efficient Adipic Acid Synthesis From Cyclohexane

, respectively. This represents the highest productivity record for the biological production of AA to date. Finally, this developed biocatalytic system is successfully employed to convert different cycloalkanes and cycloalkanols with varied carbon chain lengths into their corresponding dicarboxylic acids, highlighting its great potential as well as broad applicability for industrial applications.