Integration of Photodiagnosis and Therapy Guided by Micro/Nanorobots

Micro/Nanorobots(MNRs)integrated with phototherapy represent an emerging approach to cancer treatment and hold significant potential for addressing bacterial infections, neurological disorders, cardiovascular diseases, and related conditions. By leveraging micro/nanoscale motor systems in conjunction with phototherapy, these robots enable real-time guidance and monitoring of therapeutic processes, improving drug delivery precision and efficiency. This integration not only enhances the effectiveness of phototherapy but also minimizes damage to surrounding healthy tissues. Nevertheless, clinical translation of MNRs-assisted phototherapy still faces numerous challenges. In this review, recent key developments in the field are comprehensively summarized, the critical roles of MNRs-assisted phototherapy in clinical applications are highlighted, and insights into future directions and the pathway toward large-scale clinical implementation are provided.