Accumulation of per- and polyfluoroalkyl substances (PFAS) in tissues of wild boar (Sus scrofa)

= 8-13 in lung, spleen, muscle and heart tissues increased with molecule size, indicating passive mechanisms of distribution driven by hydrophobicity. In contrast, liver and kidney distribution coefficients scattered, indicating additional involvement of chain-length dependent active transport processes. The highest accumulation was observed for PFOS in the liver (median tissue/plasma ratio 18.0). The shortest PFAS included in the study (PFHxA, PFHpA, PFOA, PFBS and PFHxS) did not accumulate in any of the tissues, probably due to strong binding to blood proteins like serum albumin and their relative polarity impeding passive membrane diffusion.