[A cross-sectional study of prevalence of chronic kidney disease and related factors in adults in Anhui province].

Objective: To understand the prevalence of chronic kidney disease (CKD) and related factors in adults in Anhui province based on the data of Chinese Chronic Diseases and Nutrition Surveillance program (2018) in Anhui. Methods: Multi-stage stratified cluster random sampling was used to select participants aged ≥18 years. Moreover, questionnaire survey, body measurements and laboratory tests were conducted. The complex weighting method was used to estimate the prevalence of CKD in residents with different characteristics, and complex sampling data logistic regression model was used for multivariate analysis to identify related risk factors. Results: A total of 7 181 participants were included. The overall prevalence of CKD was 11.06% in adults in Anhui, and the prevalence was 12.49% in women and 9.59% in men (P<0.05). The moderate, high and very high risk for CKD progression were 8.66%, 2.02% and 0.38%, respectively. Multivariate analysis showed that age (OR=1.03, 95%CI: 1.00-1.05), BMI (OR=1.05, 95%CI: 1.01-1.09), being woman (OR=1.38,95%CI: 1.22-1.55), hypertension (OR=2.50, 95%CI: 1.76-3.56), diabetes (OR=2.28, 95%CI: 1.51-3.43), dyslipidemia (OR=1.26, 95%CI: 1.11-1.43) and hyperuricemia (OR=2.16, 95%CI: 1.68-2.78) were risk factors for CKD. Conclusion: The prevalence of CKD in adults in Anhui was relatively high and age, gender, BMI, hypertension, diabetes, dyslipidemia and hyperuricemia were found to be associated with the prevalence of CKD. To prevent CKD and its complications, attention should be paid to the management of related risk factors, including overweight and obesity, hypertension, diabetes, dyslipidemia and hyperuricemia.目的： 利用2018年安徽省中国成人慢性病与营养监测数据，比较不同特征成年居民慢性肾病（CKD）患病率，并分析其相关因素。 方法： 采用多阶段分层整群随机抽样方法，选取≥18岁居民进行询问调查、身体测量和实验室检测。使用复杂加权方法估算不同特征居民的CKD患病率，CKD患病及其相关因素的多因素分析采用复杂抽样数据logistic回归模型。 结果： 共纳入7 181人，成年居民CKD患病率为11.06%，女性CKD患病率（12.49%）高于男性（9.59%），差异有统计学意义（P<0.05）。居民CKD进展的中、高和极高风险程度比例分别为8.66%、2.02%和0.38%。多因素分析结果显示，年龄（OR=1.03，95%CI：1.00~1.05）和BMI（OR=1.05，95%CI：1.01~1.09）增加、女性（OR=1.38，95%CI：1.22~1.55）、高血压（OR=2.50，95%CI：1.76~3.56）、糖尿病（OR=2.28，95%CI：1.51~3.43）、血脂异常（OR=1.26，95%CI：1.11~1.43）和高尿酸血症（OR=2.16，95%CI：1.68~2.78）均为CKD的危险因素。 结论： 安徽省成年居民CKD患病率较高，CKD与年龄、性别、BMI、高血压、糖尿病、血脂异常和高尿酸血症相关，应当注重相关危险因素的管控，包括超重/肥胖、高血压、糖尿病、血脂异常和高尿酸血症，预防CKD及其并发症。.