The miR-195-3p/BDNF axis is a promising therapeutic for heart failure

In recent studies, Abdlay et al. found that the expression of miR-195-3p increased significantly following myocardial infarction. Both in vivo and in vitro, inhibition of miR-195-3p improved cardiac function by preventing fibrosis [ [1] Carvalho A. Ji Z. Zhang R. et al. Inhibition of miR-195-3p protects against cardiac dysfunction and fibrosis after myocardial infarction[J]. Int. J. Cardiol. 2023; 387131128 Abstract Full Text Full Text PDF PubMed Scopus (1) Google Scholar ]. This finding indicates that miR-195-3p plays a key role in cardiac disease. MiR-195-3p appears to be a promising target for the treatment of cardiac diseases.