精密医学
哮喘
医学
疾病
鉴定(生物学)
组学
重症监护医学
复杂疾病
选择(遗传算法)
生物信息学
计算机科学
病理
生物
免疫学
人工智能
植物
作者
Stefania Principe,Susanne Vijverberg,Mahmoud I. Abdel‐Aziz,Nicola Scichilone,Anke H. Maitland‐van der Zee
出处
期刊:Handbook of experimental pharmacology
日期:2022-01-01
卷期号:: 85-106
被引量:2
摘要
Asthma is a complex, heterogeneous disease that necessitates a proper patient evaluation to decide the correct treatment and optimize disease control. The recent introduction of new target therapies for the most severe form of the disease has heralded a new era of treatment options, intending to treat and control specific molecular pathways in asthma pathophysiology. Precision medicine, using omics sciences, investigates biological and molecular mechanisms to find novel biomarkers that can be used to guide treatment selection and predict response. The identification of reliable biomarkers indicative of the pathological mechanisms in asthma is essential to unravel new potential treatment targets. In this chapter, we provide a general description of the currently available -omics techniques, focusing on their implications in asthma therapy.
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