化学
维蒂希反应
串联
组合化学
曼尼希反应
有机化学
催化作用
材料科学
复合材料
作者
Hongsong Fan,Yungen Xu,Fan Yang,Shijie Xu,Xuechun Zhao,Xiaoxiang Zhang
标识
DOI:10.1002/adsc.202200323
摘要
Abstract A synthetic strategy for the construction of 2,2‐disubstituted indolin‐3‐ones from 2‐alkynylnitroarenes and ketones has been described. The corresponding indolin‐3‐one derivatives were afforded in moderate to excellent product yields by using mild conditions. After a Wittig‐like process, the key intermediates 3 H ‐indol‐3‐ones were generated from 2‐alkynylnitroarenes, which could be further transformed to the desired products through a Mannich addition. magnified image
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