Stable Isotope Measurements with Thermal and Resonance Ionization Mass Spectrometry

Thermal ionization mass spectrometry has been used extensively in the geological, nuclear and analytical sciences for stable isotope measurements. A new technique, resonance ionization mass spectrometry, offers a comprehensive approach to sensitive and selective elemental and isotopic analysis. Recent developments in thermal and resonance ionization mass spectrometry are reviewed, and specific applications of the technology to zinc and calcium metabolism studies and to trace element analysis of foodstuffs are summarized. The application potential and importance of the mass spectrometry technology to nutrition research are indicated.