化学
硒
抗菌剂
群(周期表)
组合化学
有机化学
作者
K. Kloc,Irena Maliszewska,J. Mlochowski
标识
DOI:10.1081/scc-120025191
摘要
Abstract A convenient, general method for synthesis of various 2-substituted 7-azabenzisoselenazol-3(2H)-ones having pyridine ring condensed with selenazolone moiety is presented. It is based on the conversion of 2-chloronicotinic acid into 2-(chloroseleno)nicotinic acid chloride and its reaction with primary amines. The title compounds were found in the antimicrobial assay in vitro to be highly active against broad spectrum of bacteria and fungi.
科研通智能强力驱动
Strongly Powered by AbleSci AI