小RNA
腰椎
翻译(生物学)
椎间盘
椎间盘
炎症
核心
环空(植物学)
生物
细胞生物学
解剖
信使核糖核酸
基因
遗传学
免疫学
植物
作者
Søren Ohrt-Nissen,Kristina B. V. Døssing,Maria Rossing,Christel Lajer,Jonas Vikeså,Finn Cilius Nielsen,Lennart Friis‐Hansen,Benny Dahl
标识
DOI:10.3109/03008207.2013.781594
摘要
Background data: microRNAs (miRNAs) are short ∼22 nucleotide RNA sequences that regulate messengerRNA translation. miRNAs have shown to play a role in synthesis of inflammatory mediators. Since inflammation play a role in intervertebral disk (IVD) degeneration, the objective was to isolate miRNA from human lumbar intervertebral disks and subsequently characterize the difference in miRNA expression between the annulus fibrosus (AF) and nucleus pulposus (NP).
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