坏死性下垂
细胞生物学
自噬
线粒体
细胞凋亡
生物
GPX4
癌症研究
活性氧
线粒体DNA
氧化应激
细胞
氧化磷酸化
线粒体ROS
作者
Javier García‐Bermúdez,Kıvanç Birsoy
出处
期刊:Nature
[Springer Nature]
日期:2021-05-12
卷期号:593 (7860): 514-515
被引量:23
标识
DOI:10.1038/d41586-021-01203-8
摘要
Ferroptosis is a type of cell death driven by oxidative damage to lipid membranes. The discovery that organelles called mitochondria have an antioxidant system that counteracts ferroptosis might lead to new anticancer therapies. Pathway found that combats lipid peroxidation of mitochondrial membranes.
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