Bromine is one of the important chemical raw materials. It is widely used in flame retardants, petroleum exploitation, fungicides, pesticides, photographic materials and medicine. With the increasing pressure of environmental protection, the comprehensive treatment of mother liquid from bromine extraction becomes more and more serious. In this paper, we systematically studied the composition and concentration of mother liquid from bromine extraction, compared the effect of bromine extraction process on the change of seawater composition. The experimental study focused on pH recovery and residual chlorine reduction to provide a reference for the comprehensive treatment of mother liquid from bromine extraction.