Tumor Lysis Syndrome in a Patient With Metastatic Endometrial Cancer Treated With Lattice Stereotactic Body Radiation Therapy

Spatially fractionated radiation therapy is hypothesized to allow for safe, hypofractionated, dose- escalated radiation therapy for large tumors.1-3 Spatially fractionated radiation therapy can be delivered in a grid-like pattern (ie, GRID) using 3-dimensional conformal planning techniques. It can also be delivered using intensity modulated radiation therapy (ie, lattice radiation therapy). Lattice delivers a low dose to a gross tumor volume (GTV) with high dose spherical vertices spaced within the tumor, which has previously been described in small case series of patients with gynecologic and other malignancies.