Biological properties of rare-earth doped bioactive glass

In the article, the effect of samarium ions doping on the spectroscopic and biological properties of 45S5 Bioglass® was presented. The luminescence spectra of doped glasses have been analyzed in the visible range under 405 nm laser excitation. The in vitro method for testing the apatite-forming ability of bioactive glasses was used. Crushed to 100μm fractions bioactive glasses were immersed in Simulated Body Fluid (SBF) prepared by the Kokubo method. The material was incubated at 37°C for 3 days and then the measurements of ions (Ca, Na, Si) release in SBF were carried out. The bioactivity test indicated that Sm³⁺ ions affect not only on the luminescent properties of the bioactive glasses but also their capability of creating the hydroxycarbonate-apatite (HCA) layer.