抗体
CD3型
双特异性抗体
CD28
免疫学
医学
癌症研究
T细胞
CD8型
免疫系统
单克隆抗体
作者
Dimitris Skokos,Janelle Waite,Lauric Haber,Alison Crawford,Aynur Hermann,Erica Ullman,Rabih Slim,Stephen Godin,Dharani K. Ajithdoss,Xuan Ye,Bei Wang,Qi Wu,Ilyssa Ramos,Arpita Pawashe,Lauren Canova,Kristin Vazzana,Priyanka Ram,Evan Herlihy,Hassan Ahmed,Erin Oswald
标识
DOI：10.1126/scitranslmed.aaw7888
摘要
CD28 bispecific antibodies are well tolerated and enhance the antitumor efficacy of CD3 bispecifics as a potential off-the-shelf antibody therapy.
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