化学
激进的
芳基
磺酰
催化作用
铜
组合化学
光催化
基质(水族馆)
光化学
原子转移自由基聚合
有机化学
烷基
光催化
聚合物
共聚物
海洋学
地质学
作者
Xin Zhou,Zhiyuan Peng,Peng George Wang,Qingchao Liu,Tiezheng Jia
出处
期刊:Organic Letters
[American Chemical Society]
日期:2021-01-11
卷期号:23 (3): 1054-1059
被引量:27
标识
DOI:10.1021/acs.orglett.0c04254
摘要
A synergetic copper/photoredox catalyzed ATRA of styrenes and thiosulfonates is developed. Besides aryl ethylenes, the challenging α-substituted styrenes were employed to construct the benzylic quaternary carbon centers. Owing to the mild conditions as well as the high level of substrate compability, this ATRA could be applied to derivatize bioactive natural products in late stage, and to install fluorophores across alkenes. The mechanistic studies reveal sulfonyl radicals as the key intermediate in the transformation.
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