Updates in version 2.2018 of the NCCN guidelines for pancreatic adenocarcinoma from version 1.2018 MS-1The Discussion section has been updated to reflect the changes in the algorithm. Updates in version 1.2018 of the NCCN guidelines for pancreatic adenocarcinoma from version 3.2017 GeneralChanged "narcotic" to "analgesic."Changed "Locally Advanced Unresectable" to "Locally Advanced." PANC-1Workup recommendations have been significantly revised and former PANC-2 was removed.The following options have been added to the workup: If no metastatic disease: "Consider genetic counseling and germline testing if diagnosis confirmed."If metastatic disease: "Consider genetic counseling and germline testing."Footnote "a" revised: "Multidisciplinary review should ideally involve expertise from diagnostic imaging, interventional endoscopy,