Study of Chemical Constituents from Root of Polygali fallax Hemsl II.

AIM: To investigate the bioactive constituents of Polygala fallax Hemsl. METHOD:Column chromatography was used for separation and purification.Spectral analysis was used for identification of their chemical structures. RESULT:Six compounds were isolated and their structures were identified as stigmasta 7,22 dien 3 O β D glucopyranoside(I),tenuifolin(Ⅱ),reinioside C(Ⅲ),reinioside A(Ⅳ),stigmasta 7,22 dien 3 ol(Ⅴ),and aralia cerebroside(Ⅵ). CONCLUSION: Except the compound Ⅲ,all the compounds were isolated from Polygala fallax Hemsl.for the first time.Pharmcological experiments showed that compound I and compound Ⅲ were active to bring down the sterol in the blood.