The NiTi shape memory alloy exhibits a number of remarkable properties, including shape memory, super-elasticity and resistance to fatigue and corrosion. Although Ni as a trace element contributes to the biocompatibility of NiTi alloy enriched with nickel, many experts doubt its safety after a long-time implantation. This paper reviews progress in the study on the biocompatibility of NiTi shape memory alloy and the development of porous NiTi alloy.