Objective:To observe the effect of inhibition and disinfection of Enteropathogens by Bifidobactium QJ405 and Lactobacillus QJ405 in vitro.Methods:The inhibiting test was performed on two groups:One was the testing group in which Bifidobacterium QJ405 and Lactobacillus QJ405 were cutured dlone respectively.The change of number of the bacteria had been observed at an inter of two of four hours,and the curve of bacterial grouth bad been drawn.In the disinfecting test,the metabolite of Bifidobecterium QJ405 and Lactobacillus QJ405 quantitatively inoculated respectively on the EMB agqar medium's surface which was spreaded by the quantative enteropathogens in advance,and the growing state of these bacteria was observed in the inoculated region at the following step.Results:It is obvious in our test that the grouth of hour strains of Enteropathogens and the two standard strains(ATCC2592,ATCC25923)were inhibited by Bifidobacterium QJ405 and Lactobacillus QJ405 and the merabolite of Lactobacillus QJ405 could destroy the Eneropthogens.Conclution:Bifidobacterium QJ405 and Lactobacillus QJ405 have some antibiotic effects as the probiotics.