A COMPARISON STUDY ON THE EFFICACY AND SAFETY OF ARIPIPRAZOLE AND RISPERIDONE IN THE TREATMENT OF SCHIZOPHRENIA

Objective To investigate the clinical efficacy and side effects of Aripiprazole and Risperidone in the treatment of schizophrenia. Method 100 patients with schizophrenia meeting CCMD-3 criteria were randomly divided into two groups treated with Aripiprazole or Risperidone for 8 weeks respectively. The efficacy was evaluated by PANSS and CGI-SI before and at the ends of 2,4,8 weeks in the treatment, adverse effects by TESS. Result The clinical efficacy in Aripiprazole group was similar to that in Risperidone, without significance(p0.05). Adverse effects in the Aripiprazole group was fewer than that in the Risperidone group,but it was not significant (p0.05). Conclusion Aripiprazole and Risperidone have similar efficacy in the treatment of schizophrenia.