风险分析(工程)
计算机科学
组分(热力学)
化学
业务
工程类
钥匙(锁)
法律工程学
医学
质量(理念)
作者
Oleksandra Rushchak,Vadym Sham,Bohdan Dansberg,Аndrii Kysil,Tetyana Yegorova,Pavel K. Mykhailiuk
摘要
Since 1947, the Balz-Schiemann reaction has remained the most popular method for the synthesis of meta-fluoropyridines. The method involves dangerous pyridyl diazonium salts and has led to numerous documented explosions. A safe alternative to meta-fluoropyridines has now been developed on the basis of a 1,3-disconnection strategy.
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