Design, synthesis and antifungal activity of novel 1,3,4‐Oxadiazole derivatives against Botrytis cinerea

Compound R30 is a promising lead for efficient, low-toxicity antifungal pesticides against B. cinerea. This study validates the adopted design strategy, enriches the structural diversity of ergosterol synthesis inhibitors, and provides valuable insights for sustainable control of fungal diseases and pesticide resistance. © 2026 Society of Chemical Industry.