核小体
染色质
组蛋白
超嗜热菌
组蛋白密码
超螺旋
组蛋白八聚体
生物
组蛋白H1
组蛋白H2A
遗传学
古细菌
细胞生物学
DNA
DNA复制
DNA超螺旋
基因
作者
Francesca Mattiroli,Sudipta Bhattacharyya,Pamela N. Dyer,Alison E. White,Kathleen Sandman,Brett W. Burkhart,Kyle R. Byrne,Thomas Lee,Natalie G. Ahn,Thomas J. Santangelo,John N. Reeve,Karolin Luger
出处
期刊：Science
[American Association for the Advancement of Science (AAAS)]
日期：2017-08-11
卷期号：357 (6351): 609-612
被引量：227
标识
DOI：10.1126/science.aaj1849
摘要
Origin of DNA compaction As a repeating unit in eukaryotic chromatin, a nucleosome wraps DNA in superhelical turns around a histone octamer. Mattiroli et al. present the crystal structure of an archaeal histone-DNA complex in which the histone-mediated DNA geometry is exactly the same as that in the nucleosome. Comparing features of archaeal and eukaryotic chromatin structures offers important insights into the evolution of eukaryotic nucleosomes. Science , this issue p. 609
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