Natural Products Containing a Nitrogen–Sulfur Bond

Only about 100 natural products are known to contain a nitrogen–sulfur (N–S) bond. This review thoroughly categorizes N–S bond-containing compounds by structural class. Information on biological source, biological activity, and biosynthesis is included, if known. We also review the role of N–S bond functional groups as post-translational modifications of amino acids in proteins and peptides, emphasizing their role in the metabolism of the cell.