木聚糖
戊二醛
自愈水凝胶
聚乙烯醇
材料科学
肿胀 的
化学工程
流变学
傅里叶变换红外光谱
复合材料
化学
高分子化学
有机化学
多糖
工程类
作者
Augusto Ajovalasit,Maria Antonietta Sabatino,Simona Todaro,Sabina Alessi,Daniela Giacomazza,Pasquale Picone,Marta Di Carlo,Clelia Dispenza
标识
DOI:10.1016/j.carbpol.2017.09.092
摘要
Thin xyloglucan-based hydrogel films have been synthetized and characterized in the prospect of producing wound dressings. Polyvinyl alcohol (PVA) and glycerol (Gro) were added to have an optimal combination of softness, conformability and resilience. Physical hydrogels have been transformed into permanent covalent hydrogels by reaction with glutaraldehyde (GA). Network structure-process-property relationships are discussed on the account of the results of several complementary characterizations: FTIR, rheology, thermal analysis, morphological analysis, moisture retention and swelling measurements. Selected formulations were also subjected to preliminary in vitro cytotoxicity tests. The physical and mechanical properties of some of the xyloglucan-based hydrogel films produced, combined with absence of cytotoxicity, make them suitable candidates for integration with sensors to monitor the wound healing process and further biological investigations in animal models.
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