胶质瘤
抗辐射性
生物
微泡
癌症研究
干细胞
肿瘤进展
小RNA
间充质干细胞
细胞生物学
细胞培养
癌症
遗传学
基因
作者
Xiaofan Guo,Wei Qiu,Chaochao Wang,Yanhua Qi,Boyan Li,Shaobo Wang,Rongrong Zhao,Bo Cheng,Xiao Han,Hao Du,Zijie Gao,Ziwen Pan,Shulin Zhao,Gang Li,Hao Xue
出处
期刊:Cancer Research
[American Association for Cancer Research]
日期:2023-11-14
卷期号:84 (3): 372-387
被引量:38
标识
DOI:10.1158/0008-5472.can-23-0609
摘要
Active neurons secrete exosomes enriched with miR-184-3p that promote glioblastoma progression and radioresistance by driving the proneural-to-mesenchymal transition in glioma stem cells, which can be reversed by antiseizure medication levetiracetam.
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