Bismuth is one of rare metals, its content in the Earth’s crust is 2·10-5 wt. %. The annual world consumption of bismuth is 17–21 thousand tons, and bismuth compounds account for about 77 % of this amount. Bismuth compounds applied in medicine relate to binding, coating and antacid agents (basic Bismuth subnitrate, basic Bismuth subsalicylate, Vicalin, Vicair, De-Nol, Pilorid, Xeroform, Dermatol) or antiluetic drugs (Biiochinolum, Bismoverolum).