Analysis of Factors Influencing Self‐Management Positivity in Colorectal Cancer Chemotherapy Patients Based on the ABC‐X Model: A Cross‐Sectional Study

ABSTRACT Given the high prevalence of colorectal cancer and the substantial side effects of chemotherapy, enhancing patient self‐management is of paramount importance. This study aims to identify factors influencing self‐management positivity in colorectal cancer chemotherapy patients. It also examines the mediating role of self‐regulatory fatigue in the relationship between health empowerment and self‐management positivity. A total of 302 CRC chemotherapy patients were selected from three hospitals in China. Data were collected using a general information questionnaire, the Cancer Empowerment Questionnaire, the Self‐Regulatory Fatigue Scale, and the Patient Activation Measure. The results indicate that age, primary payment source, residence, self‐regulatory fatigue, and health empowerment were identified as independent predictors of self‐management positivity. Self‐regulatory fatigue partially mediated the relationship between health empowerment and self‐management motivation, with a mediation effect of 0.120 (95% CI [0.070 ~ 0.178]), accounting for 18.94% of the total effect. In the future, healthcare professionals should pay more attention to patients' self‐regulatory fatigue and health empowerment capabilities. By implementing approaches including motivational interviewing and health education seminars, to boost patients' self‐management positivity, encourage effective self‐management behaviors, and enhance therapeutic efficacy.