医学
吸入氧分数
高氧
围手术期
优势比
麻醉
肺
机械通风
通风(建筑)
置信区间
外科
内科学
机械工程
工程类
作者
Nicholas J. Douville,Michael R. Mathis,Mark E. Smolkin,Linda W. Martin,Wanda M. Popescu,Randal S. Blank
标识
DOI:10.1213/ane.0000000000007479
摘要
The results of this study suggest a unique sensitivity to alveolar hyperoxia at the time of lung reinflation and raise the possibility that restricting the inspired oxygen fraction during lung reinflation could reduce injury and related sequelae. Our findings imply that a 10% increase in FiO 2 during the reinflation period (eg, increasing FiO 2 from 80% to 90%) would be associated with 14% greater odds of developing a postoperative pulmonary complication. However, they should be viewed as hypothesis-generating due to the retrospective nature of the study and serve as justification for prospective investigation of this association.
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