OBJECTIVE: Gut microbiota dysbiosis is closely linked to the pathogenesis of rheumatoid arthritis (RA). We aimed to identify potential probiotic gut microbes that can ameliorate the development of RA. DESIGN: T cells and macrophage polarisation were also investigated. RESULTS: . CONCLUSIONS: and ginsenoside Rg2 might represent probiotic and prebiotic agents in the treatment of RA.