胰高血糖素受体
肠促胰岛素
胰高血糖素样肽-1
兴奋剂
内科学
受体
内分泌学
能源消耗
厌食
胰高血糖素
2型糖尿病
医学
化学
胰岛素
糖尿病
体重
作者
Patrick J. Knerr,Stephanie A. Mowery,Jonathan D. Douros,Bhavesh Premdjee,Karina Rahr Hjøllund,Yantao He,Ann Maria Kruse Hansen,Annette Olsen,Diego Pérez–Tilve,Richard D. DiMarchi,Brian Finan
标识
DOI:10.1016/j.molmet.2022.101533
摘要
These pre-clinical data suggest unimolecular poly-pharmacology as an effective means to target multiple mechanisms contributing to obesity and further implicate GcgR activation as the differentiating factor between incretin receptor mono- or dual-agonists and triagonists.
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