The efficacy and safety of intense focused ultrasound in the treatment of enlarged facial pores in Asian skin

AbstractBackground: Intense focused ultrasound (IFUS) has been used successfully for skin tightening.Objective: To investigate the efficacy of IFUS in treating enlarged pores and to evaluate changes in skin elasticity and sebum production following IFUS.Materials and methods: Twenty-two subjects with enlarged pores were randomized to receive a single treatment with IFUS using 1.5-mm transducer on one side of the face, and 3.0-mm transducer on the other. Objective clinical assessments were made by blinded photographic evaluation. Subjective satisfaction and adverse effects were evaluated. Measurements of elasticity and sebum were performed at baseline, 3 and 6 weeks post-treatment.Results: Physicians' evaluation showed clinical pore improvements in 86% and 91% of the IFUS-treated sites using 1.5-mm and 3.0-mm transducer, respectively. The mean improvement scores were 1.7 and 1.9 for 1.5-mm and 3.0-mm transducer, respectively, with no statistical differences. Cutometer measurement demonstrated a significant improvement in skin elasticity. Sebum level showed a reduction without statistical significance. There was a positive correlation between improvement in elasticity and pore improvement grades. All treatments were well tolerated without significant side effects.Conclusion: IFUS using 1.5-mm or 3.0-mm transducer was safe and effective for reducing enlarged pores in Asian skin with an improvement in skin elasticity.KeywordsEnlarged facial poresintense focused ultrasoundskin elasticity Declaration of interestThe authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.